Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384652 | 0.83 | FFAR1 (0.39) | PDK1PDK2PDK3PDK4POLB | |
| SCHEMBL2233293 | 0.82 | ALDH1A1 (0.43) | CYP1A2CYP2C9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8387254 | 0.80 | KMT2A (0.42) | CYP1A2CYP2C9CYP3A4CYP2D6MAPT | |
| SCHEMBL5667645 | 0.77 | ALDH1A1 (0.47) | CYP1A2CYP2C9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8386235 | 0.77 | SLC16A3 (0.44) | CYP1A2CYP2C9KDM4ELMNACYP3A4 | |
| SCHEMBL5669097 | 0.76 | ALDH1A1 (0.46) | CYP1A2CYP2C9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5667007 | 0.75 | ALDH1A1 (0.43) | CYP1A2CYP2C9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL2835012 | 0.75 | ALDH1A1 (0.45) | CYP1A2CYP2C9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5668233 | 0.75 | ALDH1A1 (0.41) | CYP1A2CYP2C9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5669192 | 0.74 | ALDH1A1 (0.47) | CYP1A2CYP2C9SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932743-A | Methods for the solid phase synthesis of substituted indole compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1999009007-A1 | SOLID PHASE SYNTHESIS OF 2,3-DISUBSTITUTED INDOLE COMPOUNDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-25 | — | — | WO | disclosed |
| EP-0783306-A4 | METHOD FOR IMPROVING REPRODUCTIVE EFFICIENCY IN FARM ANIMALS | MERCK & CO INC (US) | 1998-09-23 | — | — | EP | disclosed |
| EP-0783306-A1 | METHOD FOR IMPROVING REPRODUCTIVE EFFICIENCY IN FARM ANIMALS | MERCK & CO. INC. (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996009824-A1 | METHOD FOR IMPROVING REPRODUCTIVE EFFICIENCY IN FARM ANIMALS | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |