Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103445 | 0.77 | TSHR (0.40) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL8383348 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL6244866 | 0.71 | — | — | |
| SCHEMBL8382914 | 0.68 | — | — | |
| SCHEMBL10158896 | 0.67 | TSHR (0.43) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL18007722 | 0.65 | TSHR (0.42) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL25509703 | 0.65 | TSHR (0.42) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL195682 | 0.64 | TSHR (0.46) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL9468778 | 0.64 | — | — | |
| SCHEMBL9055930 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |