Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA9 | Q16790 | 5/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784789 | 0.87 | TSHR (0.40) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL29703043 | 0.85 | TSHR (0.34) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL24181869 | 0.82 | TSHR (0.36) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL12006067 | 0.81 | — | — | |
| SCHEMBL10676074 | 0.79 | TSHR (0.42) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL28087699 | 0.77 | TSHR (0.40) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL6244866 | 0.74 | — | — | |
| SCHEMBL9386609 | 0.74 | TSHR (0.42) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL12988855 | 0.72 | TSHR (0.46) | TSHRLMNAHTTNPSR1HCAR2 | |
| SCHEMBL9468778 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500192-A | — | — | 2012-01-05 | — | — | JP | claimed |
| EP-2326642-A2 | SALT OF, AND PROCESSES FOR THE PREPARATION OF, 1-ISOPROPYL-4-{[4-(TETRAHYDRO-2H-PYRAN- 4-YLOXY)PHENYL]CARBONYL}HEXAHYDRO-1H-1,4-DIAZEPINE | Glaxo Group Limited (GB) | 2011-06-01 | — | — | EP | claimed |
| WO-2010018231-A2 | SALT OF, AND PROCESSES FOR THE PREPARATION OF, 1-ISOPROPYL-4-{[4-(TETRAHYDRO-2H-PYRAN- 4-YLOXY)PHENYL]CARBONYL}HEXAHYDRO-1H-1,4-DIAZEPINE | GLAXO GROUP LIMITED (GB) | 2010-02-18 | — | — | WO | claimed |
| CN-114929824-B | Sealing tape with weak adhesiveness or non-adhesiveness on one side | 德莎欧洲股份公司 | 2025-03-25 | — | — | CN | disclosed |
| US-12048710-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-30 | — | — | US | disclosed |
| US-20240228451-A1 | METHODS OF SYNTHESIZING LIPSTATIN DERIVATIVES | PANAFINA, INC. | 2024-07-11 | — | — | US | disclosed |
| EP-4326709-A1 | METHODS OF SYNTHESIZING LIPSTATIN DERIVATIVES | Panafina, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| CN-117279900-A | Synthesis method of lipstatin derivatives | 帕纳菲娜公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117241803-A | Purine nucleosides, intermediates and methods of making the same | 阿斯特罗赛特制药公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-114630828-B | Synthesis of RSV inhibition compound | 杨森科学爱尔兰无限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-20230151046-A1 | 5-POSITION MODIFIED PYRIMIDINES | NUCLERA LTD (GB) | 2023-05-18 | — | — | US | disclosed |
| US-20080051479-A1 | Fluoropolymers And Membranes Prepared From Such Polymers, In Particular For Fuel Cells and Method For Synthesizing Such Polymers | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-02-28 | — | — | US | disclosed |
| EP-1812031-A2 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-01 | — | — | EP | disclosed |
| US-20070078168-A1 | PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS | ASTRAZENECA AB (SE) | 2007-04-05 | — | — | US | disclosed |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-05-25 | — | — | US | disclosed |
| WO-2006050262-A2 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-05-11 | — | — | WO | disclosed |
| EP-1023290-A1 | SYNTHESIS OF SWAINSONINE SALTS | Glycodesign Inc. (CA) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999021858-A1 | SYNTHESIS OF SWAINSONINE SALTS | GLYCODESIGN INC. (CA) | 1999-05-06 | — | — | WO | disclosed |
| US-4843123-A | Cellular thermosetting fluorodiepoxide polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1989-06-27 | — | — | US | disclosed |
| US-4731211-A | Cellular thermosetting fluoropolymers and process for making them | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1988-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12048710-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | TSHR 1564/4885LMNA 1871/4885HTT 1834/4885 |
| US-20240228451-A1 | METHODS OF SYNTHESIZING LIPSTATIN DERIVATIVES | PNLIP, LIPC, LIPE | TSHR 2322/4885LMNA 1316/4885HTT 1503/4885 |
| US-20070078168-A1 | PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS | GCK, GCKR, GALK1 | TSHR 2945/4885LMNA 3459/4885HTT 3624/4885 |
| US-20230151046-A1 | 5-POSITION MODIFIED PYRIMIDINES | RNGTT, NSUN2, DPYD | TSHR 1763/4885LMNA 1539/4885HTT 2710/4885 |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | PTMS, QPCT, DNPEP | TSHR 935/4885LMNA 3610/4885HTT 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.