Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.58 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384220 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BNAMPTCYP2C19HRH3 | |
| SCHEMBL8385474 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BNAMPTKMT2AF10 | |
| SCHEMBL8386317 | 0.81 | EPHX2 (0.41) | ITGB3ITGA2BNAMPTKMT2AF10 | |
| SCHEMBL7762424 | 0.74 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL8386644 | 0.74 | KMT2A (0.52) | ITGB3ITGA2BNAMPTMEN1KMT2A | |
| SCHEMBL6158735 | 0.74 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL8949226 | 0.73 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL16222307 | 0.72 | EPHX2 (0.66) | NAMPTMEN1KMT2ACYP2C19HPGD | |
| SCHEMBL8312153 | 0.72 | EPHX2 (0.56) | NAMPTMEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL8385479 | 0.72 | ITGB3 (0.49) | ITGB3ITGA2BNAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |
| EP-0608759-A2 | Piperazinderivatives | MERCK PATENT GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |