Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386317 | 0.89 | EPHX2 (0.41) | ITGB3ITGA2BCYP2C19HPGDKDM4E | |
| SCHEMBL8385342 | 0.87 | ITGB3 (0.58) | ITGB3ITGA2BCYP2C19HPGDKDM4E | |
| SCHEMBL8384220 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BCYP2C19NAMPT | |
| Hydrochloric Acid SCHEMBL8949290 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BPARP1PARP2KMT2A | |
| SCHEMBL8380852 | 0.75 | CYP2C19 (0.43) | CYP2C19HPGDKDM4ENAMPTGAA | |
| SCHEMBL8384654 | 0.74 | NAMPT (0.53) | CYP2C19HPGDKDM4ENAMPTLMNA | |
| SCHEMBL8385320 | 0.74 | TGM2 (0.45) | ITGB3ITGA2BKDM4ENAMPTGAA | |
| SCHEMBL8312153 | 0.73 | EPHX2 (0.56) | CYP2C19HPGDKDM4ENAMPTGAA | |
| SCHEMBL16222307 | 0.73 | EPHX2 (0.66) | CYP2C19HPGDNAMPTKMT2ALMNA | |
| SCHEMBL8381533 | 0.72 | KMT2A (0.47) | ITGB3ITGA2BKDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |