SCHEMBL8385397

SCHEMBL8385397

C=C(C)C(=O)OCC(O)COC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13715093 0.90 TSHR (0.41) TSHRALDH1A1MEN1KMT2A
SCHEMBL8384361 0.83 TSHR (0.41) TSHRALDH1A1
SCHEMBL8389037 0.82 TSHR (0.41) TSHRMEN1KMT2A
SCHEMBL9008779 0.81 THRB (0.42) TSHRALDH1A1
SCHEMBL26082896 0.81 MEN1 (0.32) MEN1KMT2A
SCHEMBL13879034 0.80 TSHR (0.50) TSHRALDH1A1MEN1KMT2A
Acetic Acid SCHEMBL986805 0.80 KMT2A (0.34) TSHRMEN1KMT2A
SCHEMBL8385394 0.78
SCHEMBL8385399 0.78 MEN1 (0.32) MEN1KMT2A
SCHEMBL10299821 0.77 MEN1 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5892037-A Polymeric adducts of hindered amine-epoxides as stabilizers CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US disclosed
US-5665885-A FOR STABILIZING ORGANIC MATERIAL AGAINST THE DAMAGING INFLUENCE OF LIGHT, OXYGEN AND/OR HEAT CIBA-GEIGY CORPORATION (US) 1997-09-09 US disclosed
US-5637714-A OXIDATION AND HEAT RESISTANCE; PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5541274-A Polymeric adducts of hindered amine-epoxides as stabilizers CIBA-GEIGY CORPORATION (US) 1996-07-30 US disclosed
EP-0638597-A1 Polymeric adults of hindered amine-epoxydes as stabilizers CIBA-GEIGY AG (CH) 1995-02-15 EP disclosed
EP-0634399-A1 Adducts of hindered amine-epoxides as stabilisers CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed