Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PDE2A | O00408 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | PAX2 | Q02962 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491201 | 0.91 | ALDH1A1 (0.46) | TSHRKMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL4820465 | 0.90 | PDE2A (0.39) | TSHRKMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL8916197 | 0.90 | PDE2A (0.39) | TSHRKMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL4818506 | 0.89 | TSHR (0.46) | TSHRKMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL8386776 | 0.84 | TSHR (0.46) | TSHRKMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL4821987 | 0.83 | TSHR (0.40) | TSHRKMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL8916786 | 0.83 | TSHR (0.40) | TSHRKMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL5433058 | 0.83 | ALDH1A1 (0.46) | TSHRKMT2AMEN1ALDH1A1PDE2A | |
| SCHEMBL5731714 | 0.81 | PDE2A (0.47) | ALDH1A1PDE2AENPP1 | |
| SCHEMBL5434416 | 0.81 | ALDH1A1 (0.44) | TSHRKMT2AMEN1ALDH1A1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994360-A | Fungicidal 5-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-11-30 | — | — | US | claimed |
| US-5994360-A | Fungicidal 5-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-11-30 | — | — | US | disclosed |