Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX2 | Q02962 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386247 | 0.87 | TSHR (0.50) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL8912330 | 0.86 | TSHR (0.41) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL8385648 | 0.84 | TSHR (0.43) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL5593192 | 0.82 | PAX2 (0.43) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL976753 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL14270924 | 0.81 | USP2 (0.48) | TSHRALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL5593273 | 0.79 | SMN1; SMN2 (0.42) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL8390421 | 0.78 | TSHR (0.49) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL14491201 | 0.78 | ALDH1A1 (0.46) | TSHRALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL14410614 | 0.77 | PAX2 (0.47) | TSHRALDH1A1NPSR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994360-A | Fungicidal 5-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-11-30 | — | — | US | claimed |
| US-5994360-A | Fungicidal 5-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-11-30 | — | — | US | disclosed |