Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | USP28 | Q96RU2 | 3/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134108 | 0.81 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL9467111 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1MAPTGAARAB9AP2RX7 | |
| SCHEMBL8385758 | 0.81 | LMNA (0.37) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| Sulcotrione SCHEMBL29565861 | 0.79 | LMNA (0.47) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| Sulcotrione SCHEMBL55030 | 0.79 | LMNA (0.47) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| Sulcotrione SCHEMBL16899684 | 0.79 | LMNA (0.47) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL9135303 | 0.78 | LMNA (0.43) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL8019752 | 0.76 | MAPT (0.41) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL9134592 | 0.75 | LMNA (0.41) | LMNAMEN1KMT2AALDH1A1CYP2C19 | |
| Sulcotrione SCHEMBL9065438 | 0.75 | MAPT (0.43) | LMNAMEN1KMT2AALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8020573-A | — | — | None | — | — | JP | disclosed |
| EP-0666254-B1 | 2-Aroylcydohexanediones, process for their preparation and their use as herbicide or as plant growth regulating agent | BASF AG (DE) | 1999-04-14 | — | — | EP | disclosed |
| JP-H0820573-A | 2-AROYLCYCLOHEXANEDIONE AND USE AS HERBICIDE OR PLANT GROWTH-REGULATING AGENT | BASF AG | 1996-01-23 | — | — | JP | disclosed |
| EP-0666254-A1 | 2-Aroylcydohexanediones, process for their preparation and their use as herbicide or as plant growth regulating agent | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |