Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385690 | 0.81 | LMNA (0.40) | P2RX7ALDH1A1RAB9AMAPTGAA | |
| SCHEMBL7344969 | 0.75 | TSHR (0.50) | SMN1; SMN2TSHRCASP1CYP3A4ALDH1A1 | |
| SCHEMBL10815118 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRCASP1SLC6A3CYP3A4 | |
| SCHEMBL7350816 | 0.71 | SLC6A3 (0.44) | SMN1; SMN2TSHRCASP1SLC6A3CYP3A4 | |
| SCHEMBL9874230 | 0.71 | P2RX7 (0.49) | SMN1; SMN2TSHRCASP1SLC6A3CYP3A4 | |
| SCHEMBL9814786 | 0.70 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRCASP1SLC6A3CYP3A4 | |
| SCHEMBL9807671 | 0.70 | ALDH1A1 (0.45) | SMN1; SMN2TSHRCASP1ALDH1A1NPC1 | |
| SCHEMBL9807692 | 0.69 | MAPT (0.41) | SMN1; SMN2TSHRCASP1CYP3A4ALDH1A1 | |
| SCHEMBL9468045 | 0.69 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9807668 | 0.67 | TDP1 (0.42) | CYP3A4ALDH1A1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
| EP-0243313-B1 | ACYL-CYCLOHEXANE DIONES AND THEIR OXIME ETHERS EXHIBITING A HERBICIDAL AND PLANT GROWTH ACTIVITY | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | claimed |
| EP-0365484-A1 | Sulfamoyl phenyl ureas | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | claimed |
| US-4909835-A | Containing a sulfur substitution in position 5 | CIBA-GEIGY CORPORATION (US) | 1990-03-20 | — | — | US | claimed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| US-5169988-A | From unsaturated methyl ketone | CIBA-GEIGY CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| US-5132462-A | Sulfide, sulfonyl and sulfinyl compounds, agricultural use | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5026899-A | Acylcylohexanediones and the oxime ethers thereof with herbicidal and plant growth regulating properties | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0243313-B1 | ACYL-CYCLOHEXANE DIONES AND THEIR OXIME ETHERS EXHIBITING A HERBICIDAL AND PLANT GROWTH ACTIVITY | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| EP-0365484-A1 | Sulfamoyl phenyl ureas | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |
| US-4909835-A | Containing a sulfur substitution in position 5 | CIBA-GEIGY CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0243313-A1 | Acyl-cyclohexane diones and their oxime ethers exhibiting a herbicidal and plant growth activity | CIBA-GEIGY AG (CH) | 1987-10-28 | — | — | EP | disclosed |