Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 10/20 | 0.44 |
| ▸ | MMP2 | P08253 | 9/20 | 0.44 |
| ▸ | MMP1 | P03956 | 8/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | MMP7 | P09237 | 4/20 | 0.44 |
| ▸ | MMP14 | P50281 | 4/20 | 0.44 |
| ▸ | REN | P00797 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385714 | 0.93 | PSMB5 (0.46) | PSMB5MMP3MMP2MMP1MMP9 | |
| SCHEMBL6414560 | 0.89 | MMP3 (0.46) | PSMB5MMP3MMP2MMP1MMP9 | |
| SCHEMBL6419064 | 0.88 | MMP3 (0.46) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7384875 | 0.85 | MMP1 (0.58) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7427129 | 0.85 | MMP1 (0.58) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL6415164 | 0.85 | MMP1 (0.58) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7898741 | 0.85 | MMP1 (0.58) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL8764329 | 0.82 | MMP1 (0.58) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7381282 | 0.82 | MMP1 (0.58) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL6416194 | 0.82 | MMP1 (0.58) | MMP3MMP2MMP1MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-B1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | DARWIN DISCOVERY LTD (GB) | 1999-04-28 | — | — | EP | claimed |