SCHEMBL8385776

SCHEMBL8385776

C[Si](CCc1ccccc1)(CCc1ccccc1)[SiH2][SiH3]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
KCNH2 Q12809 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39
ATM Q13315 1/20 0.39
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
AOC3 Q16853 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8384955 0.78 TDP1 (0.52) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL3389806 0.75 TDP1 (0.52) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL6420860 0.75 TDP1 (0.52) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL16550634 0.75 TDP1 (0.52) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL7277179 0.71 TDP1 (0.48) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL523393 0.71 TDP1 (0.48) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL8384979 0.71 TDP1 (0.48) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL8384621 0.71 TDP1 (0.48) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL680098 0.71 TDP1 (0.54) TDP1KCNH2ALDH1A1HPGDALOX15
SCHEMBL10431545 0.71 TDP1 (0.54) TDP1KCNH2ALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed