SCHEMBL523393

SCHEMBL523393

C[Si](Cl)(Cl)CCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
ALDH1A1 P00352 4/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
AOC3 Q16853 2/20 0.43
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
ATM Q13315 1/20 0.43
NPC1 O15118 1/20 0.43
KDM1A O60341 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
HTR1A P08908 1/20 0.43
ADRA2A P08913 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899074 0.87 CA2 (0.35) TDP1TAAR1AOC3NPC1LMNA
SCHEMBL524107 0.86 L3MBTL1 (0.45) AOC3MAOAMAOBHTR1AADRA2A
SCHEMBL523595 0.86 TDP1 (0.48) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL1204279 0.85 L3MBTL1 (0.48) MAOAMAOB
SCHEMBL22555480 0.83 SIGMAR1 (0.50) MAOAMAOB
SCHEMBL10000437 0.83 SIGMAR1 (0.50) MAOAMAOB
SCHEMBL9322667 0.82 TDP1 (0.44) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL3389806 0.80 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL208903 0.80 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL16550634 0.80 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430782-B Resin for high-brightness pore-free polyurethane sole, and preparation method and application thereof 山东一诺威聚氨酯股份有限公司 2024-04-19 CN claimed
CN-117430782-A Resin for high-brightness pore-free polyurethane sole, and preparation method and application thereof 山东一诺威聚氨酯股份有限公司 2024-01-23 CN claimed
US-11485677-B2 Textured glass articles and methods of making the same CORNING INCORPORATED (US) 2022-11-01 US claimed
US-20200407270-A1 TEXTURED GLASS ARTICLES AND METHODS OF MAKING THE SAME CORNING INCORPORATED 2020-12-31 US claimed
WO-2020264232-A2 TEXTURED GLASS ARTICLES AND METHODS OF MAKING THE SAME CORNING INCORPORATED (US) 2020-12-30 WO claimed
CN-107207884-A Weather-proof, antimycotic, anti-coloring pollution coating and the method being applied on timber, masonry material or other porous materials 休斯敦大学系统 2017-09-26 CN claimed
CN-107208354-A Anti-soiling, anti-staining coating and method of applying to textile or other flexible material 休斯敦大学系统 2017-09-26 CN claimed
CN-107109777-A Antifouling, anti-coloring pollution the method applied without fluorine coating and on material 休斯敦大学系统 2017-08-29 CN claimed
WO-2014170799-A1 CROSSLINKABLE VARNISH AND METHOD FOR APPLYING SAME COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-10-23 WO claimed
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US claimed
US-7704432-B2 Imprint lithographic method for making a polymeric structure AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-04-27 US claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
US-5734043-A POLYSACCHARIDE SUPPORTED ON SILICA GEL DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-31 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
US-4997899-A Organosilicon or germanium polymers NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-03-05 US claimed
US-4839451-A Processes for the preparation of polysilylenes XEROX CORPORATION (US) 1989-06-13 US claimed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
US-4099981-A MINERAL FILLER UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed
US-4044037-A COUPLING AGENTS UNION CARBIDE CORPORATION (US) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 TDP1 2376/4885ALDH1A1 3642/4885HPGD 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.