Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28122273 | 0.89 | KMT2A (0.58) | LCKFYNDAOALDH1A1CES2 | |
| SCHEMBL2166098 | 0.89 | CES2 (0.71) | LCKFYNDAOALDH1A1CES2 | |
| Oxalic Acid SCHEMBL6968596 | 0.86 | LCK (0.67) | LCKFYNDAOALDH1A1CES2 | |
| Oxalic Acid SCHEMBL7445055 | 0.84 | LCK (0.64) | LCKFYNDAOALDH1A1CES2 | |
| Oxalic Acid SCHEMBL6968894 | 0.84 | LCK (0.64) | LCKFYNDAOALDH1A1CES2 | |
| SCHEMBL6966883 | 0.81 | LMNA (0.62) | LCKFYNDAOCES2CES1 | |
| SCHEMBL9260845 | 0.80 | AKR1C3 (0.62) | LCKFYNDAOALDH1A1CES2 | |
| SCHEMBL17100305 | 0.79 | CES2 (0.54) | LCKFYNDAOCES2CES1 | |
| SCHEMBL31612030 | 0.79 | CES2 (0.54) | LCKFYNDAOALDH1A1CES2 | |
| SCHEMBL20448559 | 0.79 | SRD5A2 (0.55) | LCKFYNDAOCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112442008-A | Method for preparing 1, 4-dithiine and thiophene compounds by regulating elemental sulfur and active internal alkyne at temperature and conversion reaction of compound | 华南理工大学 | 2021-03-05 | — | — | CN | claimed |
| US-6096124-A | Ink compositions | XEROX CORPORATION (US) | 2000-08-01 | — | — | US | claimed |
| CN-113045530-B | Method for preparing naphthopyran compounds by ruthenium catalysis | 成都大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-112442008-B | Method for preparing 1, 4-dithiine and thiophene compounds by regulating elemental sulfur and active internal alkyne at temperature and conversion reaction of compound | 华南理工大学 | 2022-05-27 | — | — | CN | disclosed |
| EP-3162799-B1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2021-03-10 | — | — | EP | disclosed |
| CN-112442008-A | Method for preparing 1, 4-dithiine and thiophene compounds by regulating elemental sulfur and active internal alkyne at temperature and conversion reaction of compound | 华南理工大学 | 2021-03-05 | — | — | CN | disclosed |
| US-10696640-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| CN-106573896-B | Fluoroalkylating agents | KUMIAI CHEMICAL INDUSTRY CO.,LTD. (JP) | 2019-11-01 | — | — | CN | disclosed |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10308613-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| EP-0268396-B1 | 4-(BENZOYL)THIOPHENE(OR FURAN)-SULFONAMIDE AND DERIVATIVES THEREOF FOR THE TOPICAL TREATMENT OF ELEVATED INTRAOCULAR PRESSURES | MERCK & CO. INC. (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0140540-B1 | PHOTOCHROMIC COMPOUNDS AND THEIR USES IN PHOTOREACTIVE LENSES | THE PLESSEY COMPANY plc (GB) | 1990-05-09 | — | — | EP | disclosed |
| EP-0268396-A1 | 4-(benzoyl)thiophene(or furan)-sulfonamide and derivatives thereof for the topical treatment of elevated intraocular pressures | MERCK & CO. INC. (US) | 1988-05-25 | — | — | EP | disclosed |
| US-4685783-A | Polychromic tetracyclo-spiro-adamatylidene derivatives, and polychromic lens incorporating said compounds | THE PLESSEY COMPANY P.L.C. (GB) | 1987-08-11 | — | — | US | disclosed |
| EP-0140540-A2 | Photochromic compounds and their uses in photoreactive lenses | THE PLESSEY COMPANY plc (GB) | 1985-05-08 | — | — | EP | disclosed |
| US-4477635-A | Polymeric triarylmethane dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| EP-0070039-A2 | Polymerization catalyst and process for polymerizing alpha-olefins | PHILLIPS PETROLEUM COMPANY (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4243552-A | MAGNESIUM CHLORIDE OR MANGANESE CHLORIDE AND ADJUVANT | PHILLIPS PETROLEUM COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| EP-0012397-A1 | Polymerization catalyst and process for polymerizing alpha-olefins | PHILLIPS PETROLEUM COMPANY (US) | 1980-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308613-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | LCK 1400/4885FYN 743/4885DAO 2296/4885 |
| US-10696640-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | LCK 1400/4885FYN 743/4885DAO 2296/4885 |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | LCK 1400/4885FYN 743/4885DAO 2296/4885 |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | LCK 1400/4885FYN 743/4885DAO 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.