⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970324 | 0.85 | TSHR (0.35) | — | |
| SCHEMBL5449385 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL6973642 | 0.81 | CA12 (0.35) | — | |
| SCHEMBL1793940 | 0.78 | CA12 (0.33) | — | |
| SCHEMBL1704328 | 0.73 | CA12 (0.36) | — | |
| SCHEMBL8566874 | 0.71 | MAPT (0.35) | — | |
| SCHEMBL9421748 | 0.71 | DNM1 (0.42) | — | |
| SCHEMBL2426474 | 0.71 | — | — | |
| SCHEMBL6968769 | 0.69 | TSHR (0.32) | — | |
| SCHEMBL6975507 | 0.69 | CA12 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271713-B1 | LOW VISCOSITY, HIGH MOLECULAR WEIGHT LINEAR RANDOM-BLOCK SILICONE POLYALKYLENEOXIDE COPOLYMERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-02-18 | — | — | EP | claimed |
| EP-2271713-A2 | LOW VISCOSITY, HIGH MOLECULAR WEIGHT LINEAR RANDOM-BLOCK SILICONE POLYALKYLENEOXIDE COPOLYMERS | Momentive Performance Materials Inc. (US) | 2011-01-12 | — | — | EP | claimed |
| US-7851548-B2 | made from epoxy-functional siloxanes and epoxy-functional polyalkylene oxides, with linkages that include optionally quaternized amine groups; textile enhancers, fabric softeners, hair conditioners; low viscosity is obtained through the absence of H-bonding association with pendant hydroxyl groups | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-12-14 | — | — | US | claimed |
| CN-101106990-B | Compounds and compositions as protein kinase inhibitors | IRM LLC | 2010-12-08 | — | — | CN | claimed |
| WO-2009134364-A2 | LOW VISCOSITY, HIGH MOLECULAR WEIGHT LINEAR RANDOM-BLOCK SILICONE POLYALKYLENEOXIDE COPOLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-11-05 | — | — | WO | claimed |
| US-20090274643-A1 | Low viscosity, high molecular weight linear random-block silicone polyalkyleneoxide copolymers | MOMENTIVE PERFORMANCE MATERIALS INC. | 2009-11-05 | — | — | US | claimed |
| US-20090105250-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-04-23 | — | — | US | claimed |
| CN-101106990-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2008-01-16 | — | — | CN | claimed |
| EP-1841431-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM, LLC (BM) | 2007-10-10 | — | — | EP | claimed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | claimed |
| US-6514977-B1 | For treating p38 kinase mediated disorders | G.D. SEARLE & COMPANY | 2003-02-04 | — | — | US | claimed |
| US-6423713-B1 | Substituted pyrazoles as p38 kinase inhibitors | G. D. SEARLE & COMPANY | 2002-07-23 | — | — | US | claimed |
| US-20020045574-A1 | Glycopeptide antibacterial compounds and methods of using same | PRINCETON UNIVERSITY | 2002-04-18 | — | — | US | claimed |
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | claimed |
| EP-1144403-A1 | SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-10-17 | — | — | EP | claimed |
| EP-0679691-B1 | Cationic or basic aminobenzthiazole dyestuffs | CIBA SC HOLDING AG (CH) | 2001-09-05 | — | — | EP | claimed |
| EP-1123932-A1 | NOVEL ANTHRAPYRIDONE COMPOUNDS, WATER-BASED MAGENTA INK COMPOSITION, AND METHOD OF INK-JET PRINTING | Nippon Kayaku Kabushiki Kaisha (JP) | 2001-08-16 | — | — | EP | claimed |
| WO-2000031063-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-06-02 | — | — | WO | claimed |
| US-5635607-A | BLUE OR VIOLET COLOR DYE FOR DYEING PAPER, TEXTILES | CIBA-GEIGY CORPORATION (US) | 1997-06-03 | — | — | US | claimed |
| EP-0679691-A2 | Cationic or basic aminobenzthiazole dyestuffs | CIBA-GEIGY AG (CH) | 1995-11-02 | — | — | EP | claimed |