Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793940 | 0.88 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL838600 | 0.85 | — | — | |
| SCHEMBL6973642 | 0.84 | CA12 (0.35) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL6968769 | 0.84 | TSHR (0.32) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL6974455 | 0.80 | — | — | |
| SCHEMBL6973884 | 0.79 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL6975507 | 0.74 | CA12 (0.35) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL1704328 | 0.72 | CA12 (0.36) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL7472255 | 0.72 | DNM1 (0.32) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8566874 | 0.70 | MAPT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |