Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697165 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL437760 | 0.75 | TDP1 (0.32) | TDP1 | |
| SCHEMBL28161659 | 0.74 | LMNA (0.39) | LMNAL3MBTL1TDP1 | |
| SCHEMBL28541083 | 0.72 | TSHR (0.35) | LMNATDP1 | |
| SCHEMBL13572010 | 0.71 | THRB (0.33) | LMNA | |
| SCHEMBL29170454 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL3680185 | 0.69 | TSHR (0.35) | LMNA | |
| SCHEMBL1619993 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL27854699 | 0.67 | — | — | |
| SCHEMBL546820 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891914-A | COMPLEX OF ORGANOSILICON COMPOUND AND ACTIVE MATERIALS | SPECIAL ADVANCED BIOMATERIALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5686065-A | Topical siloxane sunscreen compositions having enhanced performance and safety | SPECIAL ADVANCED BIOMATERIALS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1992017184-A2 | BIOACTIVE TOPICAL SILOXANE COMPOSITIONS HAVING ENHANCED PERFORMANCE AND SAFETY | SPECIAL ADVANCED BIOMATERIALS, INC. (US) | 1992-10-15 | — | — | WO | disclosed |