SCHEMBL838699

SCHEMBL838699

CCNC(Cc1ccc(F)cc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
ACE P12821 3/20 0.51
CA2 P00918 1/20 0.49
MME P08473 3/20 0.48
CPA1 P15085 3/20 0.48
ACE2 Q9BYF1 2/20 0.48
FOLH1 Q04609 3/20 0.47
GPR34 Q9UPC5 2/20 0.46
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
POLB P06746 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KMT2A Q03164 1/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30062839 1.00 ALDH1A1 (0.57) ALDH1A1ACECA2MMECPA1
SCHEMBL11150853 0.87 ALDH1A1 (0.51) ALDH1A1ACECA2MMECPA1
SCHEMBL12301662 0.85 ALDH1A1 (0.46) ALDH1A1ACECA2MMECPA1
SCHEMBL11409509 0.85 ALDH1A1 (0.46) ALDH1A1ACECA2CA12CA7
SCHEMBL14374198 0.85 ALDH1A1 (0.46) ALDH1A1ACECA2MMECPA1
SCHEMBL547121 0.85 FOLH1 (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL547122 0.85 FOLH1 (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL1287829 0.85 FOLH1 (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL25764849 0.85 TDP1 (0.52) ACEMMECPA1ACE2FOLH1
SCHEMBL1098155 0.85 ALDH1A1 (0.62) ALDH1A1ACECA2MMECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178486-A Asymmetric hydrogenation synthesis method and application of non-natural polypeptide 西南大学 2023-05-30 CN disclosed
CN-107810189-B Process for the preparation of nitrogen mustard derivatives 肿瘤多肽股份公司 2022-02-11 CN disclosed
WO-2021093817-A1 IMMUNOMODULATORY COMPOUNDS, COMPOSITION AND APPLICATION THEREOF 杭州和正医药有限公司 2021-05-20 WO disclosed
US-8143052-B2 Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium UBE INDUSTRIES, LTD. (JP) 2012-03-27 US disclosed