Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 13/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753883 | 0.69 | KMT2A (0.41) | ALDH1A1POLB | |
| SCHEMBL7943945 | 0.65 | KMT2A (0.39) | — | |
| SCHEMBL5754313 | 0.65 | MEN1 (0.37) | TP53ALDH1A1LMNAPOLB | |
| SCHEMBL7944027 | 0.65 | GAA (0.32) | — | |
| SCHEMBL8102083 | 0.59 | GAA (0.44) | ALDH1A1 | |
| SCHEMBL6576018 | 0.58 | BACE1 (0.58) | ALDH1A1LMNAADORA2A | |
| SCHEMBL7655306 | 0.58 | HPGD (0.53) | ALDH1A1LMNAPOLBADORA2A | |
| SCHEMBL5753908 | 0.55 | LMNA (0.42) | ALDH1A1LMNAPOLB | |
| SCHEMBL19667559 | 0.55 | KMT2A (0.57) | ALDH1A1LMNA | |
| SCHEMBL25286042 | 0.54 | GAA (0.45) | ALDH1A1POLBL3MBTL1SLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869509-A | TREAT DISORDERS RESPONSIVE TO OPENERS OF THE LARGE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-02-09 | — | — | US | disclosed |