Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | F2R | P25116 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385996 | 0.74 | DHFR (0.43) | DHFRSLC2A1KCNH2MEN1ALDH1A1 | |
| SCHEMBL9575141 | 0.74 | DHFR (0.46) | DHFRSLC2A1KCNH2DCPS | |
| SCHEMBL21067727 | 0.72 | DHFR (0.54) | DHFRSLC2A1DCPS | |
| SCHEMBL4689980 | 0.70 | DHFR (0.47) | DHFRSLC2A1F2RPTPN11 | |
| SCHEMBL8389989 | 0.70 | DCPS (0.51) | DHFRSLC2A1KCNH2DCPSMEN1 | |
| SCHEMBL4029524 | 0.70 | DHFR (0.49) | DHFRSLC2A1KCNH2DCPSMEN1 | |
| SCHEMBL4689002 | 0.69 | DHFR (0.37) | DHFRSLC2A1PTPN11MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6600020 | 0.69 | DHFR (0.47) | DHFRSLC2A1KCNH2DCPSMEN1 | |
| Hydrochloric Acid SCHEMBL6603234 | 0.69 | DHFR (0.47) | DHFRSLC2A1KCNH2DCPSMEN1 | |
| Hydrochloric Acid SCHEMBL27593037 | 0.69 | DHFR (0.47) | DHFRSLC2A1KCNH2DCPSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018980-A1 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES | FMC CORPORATION (US) | 1994-09-01 | — | — | WO | claimed |
| US-5874579-A | Insecticidal substituted-2.4-diaminoquinazolines related applications | FMC CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| US-5616718-A | USEFUL FOR MAKING 2,4-DIAMINOQUINAZOLINES; INSECTICIDES | FMC CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |
| US-5534518-A | Insecticidal substituted-2,4-diaminoquinazolines | FMC CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0684824-A4 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES. | FMC CORP (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0684824-A1 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES | FMC CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018980-A1 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES | FMC CORPORATION (US) | 1994-09-01 | — | — | WO | disclosed |