Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433550 | 0.77 | KMT2A (0.54) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL4366146 | 0.77 | KMT2A (0.54) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8581308 | 0.77 | HPGD (0.52) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8581311 | 0.77 | HPGD (0.52) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL3421548 | 0.77 | KMT2A (0.54) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL16863924 | 0.75 | KDM4E (0.54) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8733487 | 0.74 | TSHR (0.45) | HPGDSMN1; SMN2TSHRHTT | |
| SCHEMBL18084165 | 0.73 | NPC1 (0.45) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL10580663 | 0.73 | NPC1 (0.45) | NPC1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL3310675 | 0.72 | KMT2A (0.61) | NPC1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852592-B1 | THERMOPLASTIC POLYURETHANES CONTAINING UNITS OF AN AROMATIC DIOL | DOW CHEMICAL CO (US) | 1999-05-06 | — | — | EP | claimed |