Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546578 | 0.89 | TRPA1 (0.41) | TSHRACHECHRM3HPGDHTT | |
| SCHEMBL7925207 | 0.86 | NPC1 (0.42) | CHRM3HPGDERCC5FEN1SMN1; SMN2 | |
| SCHEMBL6548199 | 0.86 | NPC1 (0.42) | CHRM3HPGDERCC5FEN1SMN1; SMN2 | |
| SCHEMBL6546142 | 0.86 | CHRM3 (0.39) | TSHRACHECHRM3HPGDERCC5 | |
| SCHEMBL6546582 | 0.85 | NFE2L2 (0.46) | TSHRCHRM3HTTSMN1; SMN2 | |
| SCHEMBL6546899 | 0.84 | HPGD (0.45) | TSHRHPGDERCC5FEN1HTT | |
| SCHEMBL20764187 | 0.82 | MAPK14 (0.40) | CHRM3HTT | |
| SCHEMBL22359706 | 0.82 | CYP3A4 (0.45) | TSHRCHRM3HPGDMAOAMAOB | |
| SCHEMBL516741 | 0.80 | MAOA (0.41) | TSHRACHECHRM3HPGDERCC5 | |
| SCHEMBL18608222 | 0.77 | HPGD (0.45) | TSHRACHEHPGDERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858339-A1 | A METHOD OF TREATING FILARIAE | NOVO NORDISK A/S (DK) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997017073-A1 | A METHOD OF TREATING FILARIAE | NOVO NORDISK A/S (DK) | 1997-05-15 | — | — | WO | disclosed |