Tautomycin

Tautomycin

SCHEMBL83891

CO[C@H]([C@H](O)CC(=O)[C@@H](C)[C@@H](O)CC[C@@H](C)[C@@H]1O[C@]2(CC[C@@H](C)[C@H](CC[C@H](C)C(C)=O)O2)CC[C@@H]1C)[C@H](OC(=O)C[C@@H](O)C1=C(C)C(=O)OC1=O)C(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPA Q15257 5/20 1.00
PPP2CA P67775 4/20 1.00
PPP5C P53041 2/20 1.00
PTPN1 P18031 1/20 1.00
PPP1CC P36873 11/20 0.71
ALDH1A1 P00352 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tautomycin SCHEMBL23008660 1.00 PTPA (1.00) PTPAPPP2CAPPP5CPTPN1PPP1CC
Tautomycin SCHEMBL23008659 1.00 PTPA (1.00) PTPAPPP2CAPPP5CPTPN1PPP1CC
Tautomycin SCHEMBL22965087 1.00 PTPA (1.00) PTPAPPP2CAPPP5CPTPN1PPP1CC
Tautomycin SCHEMBL21298444 1.00 PTPA (1.00) PTPAPPP2CAPPP5CPTPN1PPP1CC
SCHEMBL21298445 0.80 PTPA (0.66) PTPAPPP2CAPPP5CPTPN1PPP1CC
SCHEMBL24974804 0.77 PPP2CA (0.62) PTPAPPP2CAPPP5CPTPN1PPP1CC
SCHEMBL820638 0.58 PPP2CA (0.76) PTPAPPP2CAPPP5CPTPN1PPP1CC
SCHEMBL15381937 0.57 PPP2CA (0.57) PTPAPPP2CAPPP5CPTPN1PPP1CC
SCHEMBL15381933 0.57 PPP2CA (0.88) PTPAPPP2CAPPP5CPTPN1PPP1CC
SCHEMBL15381938 0.56 PPP2CA (0.90) PTPAPPP2CAPPP5CPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564486-B2 Devices and methods for treating an aneurysm MERLIN MD PTE LTD. (SG) 2026-03-03 US claimed
EP-4683654-A1 SIRP VARIANTS AND USES THEREOF Li, Wangzhi (US) 2026-01-28 EP claimed
EP-4673458-A1 METHODS OF ENHANCING PRODUCTION OF METABOLITES IN BACTERIA JOHN INNES CENTRE (GB) 2026-01-07 EP claimed
EP-3966344-B1 KINASE SCREENING ASSAYS UNIV NEWCASTLE (GB) 2025-06-25 EP claimed
WO-2024213119-A1 PH-SENSITIVE CD47-BINDING DOMAINS AND USES THEREOF ADAPTOCUE, LLC (US) 2024-10-17 WO claimed
WO-2024193635-A1 SIRP VARIANTS AND USES THEREOF LI, Wangzhi (US) 2024-09-26 WO claimed
WO-2024180095-A1 METHODS OF ENHANCING PRODUCTION OF METABOLITES IN BACTERIA JOHN INNES CENTRE (GB) 2024-09-06 WO claimed
US-12064426-B2 Selective inhibitors of ROCK1 and ROCK2 protein kinases and uses thereof Genosco Inc. (US) 2024-08-20 US claimed
WO-2024085786-A1 MEDIUM AND DEVICE FOR COLLECTING, STORING AND TRANSPORTING Gra Olga Alekseevna (RU) 2024-04-25 WO claimed
EP-4356731-A1 MEDIUM AND DEVICE FOR COLLECTING, STORING AND TRANSPORTING BIOLOGICAL SAMPLES, AS WELL AS THEIR USE FOR THE STABILIZATION OF EXTRACELLULAR NUCLEIC ACIDS Gra, Olga Alekseevna (RU) 2024-04-24 EP claimed
WO-2004010900-A1 DEVICES DELIVERING THERAPEUTIC AGENTS AND METHODS REGARDING THE SAME AVANTEC VASCULAR CORPORATION (US) 2004-02-05 WO claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-0696730-B1 Use of an inhibitor of serine/threonine protein phosphatases to induce premature chromosome condensation (PCC) GOTOH EISUKE (JP) 2002-11-06 EP claimed
JP-2002525268-A 2002-08-13 JP claimed
US-20020061303-A1 Inhibitors of angiogenesis and tumor growth for local and systemic administration SINGH, SAIRA SAYED 2002-05-23 US claimed
WO-2002028387-A1 INHIBITORS OF ANGIOGENESIS AND TUMOR GROWTH FOR LOCAL AND SYSTEMIC ADMINISTRATION ONCOPHARMACEUTICAL, INC. (US) 2002-04-11 WO claimed
US-20020012703-A1 Treatment of oncologic tumors with an injectable formulation of a golgi apparatus disturbing agent SINGH, SAIRA SAYED 2002-01-31 US claimed
EP-1114144-A1 TREATMENT OF ONCOLOGIC TUMORS WITH AN INJECTABLE FORMULATION OF A GOLGI APPARATUS DISTURBING AGENT Oncopharmaceutical, Inc. (US) 2001-07-11 EP claimed
WO-2000015766-A1 TREATMENT OF ONCOLOGIC TUMORS WITH AN INJECTABLE FORMULATION OF A GOLGI APPARATUS DISTURBING AGENT ONCOPHARMACEUTICAL, INC. (US) 2000-03-23 WO claimed
EP-0696730-A1 Agents and a method of chromosome preparation using protein phosphatase inhibitors induced premature chromosome condensation (PCC) technique Gotoh, Eisuke (JP) 1996-02-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12064426-B2 Selective inhibitors of ROCK1 and ROCK2 protein kinases and uses thereof ROCK2, ROCK1, MYLK3 PTPA 762/4885PPP2CA 300/4885PPP5C 148/4885
US-12564486-B2 Devices and methods for treating an aneurysm PDE1B, SMCHD1, PDE1C PTPA 1892/4885PPP2CA 3375/4885PPP5C 2350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.