Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LCT | P09848 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.30 |
| ▸ | FEN1 | P39748 | 4/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387171 | 0.90 | GBA1 (0.33) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8390781 | 0.89 | NAAA (0.35) | HTR1ASLC6A2SLC6A4SLC6A3NAAA | |
| SCHEMBL8385968 | 0.88 | FFAR4 (0.35) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8385977 | 0.85 | ALOX5AP (0.38) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8390766 | 0.83 | FFAR4 (0.34) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL7028333 | 0.83 | NAAA (0.34) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8389623 | 0.81 | FFAR4 (0.32) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8387321 | 0.81 | LTB4R2 (0.35) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8385815 | 0.80 | FFAR4 (0.33) | GBA1LCTUGCGGBA2MGAM | |
| SCHEMBL8385805 | 0.79 | GBA1 (0.31) | GBA1LCTUGCGGBA2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888423-A | Fluorobenzyl ether derivatives | ROLIC AG (CH) | 1999-03-30 | — | — | US | disclosed |