Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | LCT | P09848 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732551 | 0.91 | GBA1 (0.37) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL7033562 | 0.89 | GBA1 (0.34) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8727651 | 0.89 | GBA1 (0.39) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8725535 | 0.88 | NAAA (0.35) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL7024343 | 0.88 | NAAA (0.35) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8387253 | 0.87 | KDM5A (0.34) | KDM5AKDM4CKDM5B | |
| SCHEMBL7033040 | 0.87 | KDM5A (0.34) | KDM5AKDM4CKDM5B | |
| SCHEMBL7027057 | 0.87 | FFAR4 (0.33) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL7028248 | 0.84 | NAAA (0.36) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8389609 | 0.83 | GBA1 (0.32) | NAAAGBA1LCTUGCGGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |