Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL4601763 | 0.87 | HDAC8 (0.55) | HDAC4HDAC2HDAC8ACHERXRA | |
| SCHEMBL348758 | 0.87 | ACHE (0.55) | HDAC4HDAC2HDAC8ACHEKCNK3 | |
| SCHEMBL29714909 | 0.87 | ACHE (0.55) | HDAC4HDAC2HDAC8ACHEKCNK3 | |
| Water SCHEMBL27710899 | 0.85 | ACHE (0.52) | HDAC4HDAC2HDAC8ACHEKCNK3 | |
| SCHEMBL1543017 | 0.83 | HDAC4 (0.47) | HDAC4HDAC2HDAC8ACHEKCNK3 | |
| SCHEMBL11139433 | 0.83 | HDAC8 (0.47) | HDAC4HDAC2HDAC8ACHEKCNK3 | |
| O-Xylene SCHEMBL7844997 | 0.79 | ACHE (0.46) | HDAC4HDAC2HDAC8ACHEKCNK3 | |
| SCHEMBL18378184 | 0.79 | ACHE (0.50) | ACHELMNAPTPN5CNR1CNR2 | |
| Phosphoric Acid SCHEMBL27558416 | 0.78 | HDAC8 (0.43) | HDAC4HDAC2HDAC8ACHEKCNK3 | |
| Phosphoric Acid SCHEMBL27558610 | 0.78 | HDAC8 (0.43) | HDAC4HDAC2HDAC8ACHEKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558040-B1 | Process for stabilizing organophosphorus compounds | ALBEMARLE CORP (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0558040-A2 | Process for stabilizing organophosphorus compounds | ALBEMARLE CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |