SCHEMBL348758

SCHEMBL348758

Cc1cccc(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.55
HDAC4 P56524 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
TSHR P16473 1/20 0.48
KIF11 P52732 3/20 0.47
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
KCNH2 Q12809 1/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 1/20 0.44
POLB P06746 1/20 0.42
KCNK3 O14649 1/20 0.42
CNR1 P21554 2/20 0.42
CNR2 P34972 2/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29714909 1.00 ACHE (0.55) ACHEHDAC4HDAC2HDAC8TSHR
Water SCHEMBL27710899 0.97 ACHE (0.52) ACHEHDAC4HDAC2HDAC8TSHR
SCHEMBL11139433 0.91 HDAC8 (0.47) ACHEHDAC4HDAC2HDAC8TSHR
SCHEMBL1543017 0.91 HDAC4 (0.47) ACHEHDAC4HDAC2HDAC8TSHR
O-Xylene SCHEMBL7844997 0.91 ACHE (0.46) ACHEHDAC4HDAC2HDAC8TSHR
Phosphonic Acid SCHEMBL8389883 0.87 HDAC4 (0.48) ACHEHDAC4HDAC2HDAC8KIF11
Phenol SCHEMBL28119910 0.85 ACHE (0.54) ACHEHDAC4HDAC2HDAC8KIF11
Phosphoric Acid SCHEMBL27558416 0.85 HDAC8 (0.43) ACHEHDAC4HDAC2HDAC8TSHR
Phosphoric Acid SCHEMBL27558610 0.85 HDAC8 (0.43) ACHEHDAC4HDAC2HDAC8TSHR
SCHEMBL8784697 0.84 ACHE (0.55) ACHEKIF11CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 679 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584277-A1 BIS (ARENE) METAL COMPLEXES AND RELATED METHODS Entegris, Inc. (US) 2025-07-16 EP claimed
CN-119968378-A Bis (aromatic hydrocarbon) metal complexes and related methods 恩特格里斯公司 2025-05-09 CN claimed
CN-119874471-A Preparation method and application of p-tert-butyltoluene 中国石油化工股份有限公司 2025-04-25 CN claimed
EP-4476233-A1 ORGANOMETALLIC PRECURSORS AND RELATED METHODS Entegris, Inc. (US) 2024-12-18 EP claimed
CN-118804919-A Organometallic precursors and related methods 恩特格里斯公司 2024-10-18 CN claimed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
US-20240109927-A1 BIS (ARENE) METAL COMPLEXES AND RELATED METHODS ENTEGRIS, INC. 2024-04-04 US claimed
WO-2024054387-A1 BIS (ARENE) METAL COMPLEXES AND RELATED METHODS ENTEGRIS, INC. (US) 2024-03-14 WO claimed
US-20230278958-A1 TRICYCLIC HETEROCYCLES MERCK PATENT GMBH (DE) 2023-09-07 US claimed
WO-2010108874-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3 TERT.-BUTYL BENZALDEHYDE- DIMETHYLACETAL BASF SE (DE) 2010-09-30 WO claimed
EP-0714902-B1 Rhenium and aluminium compounds, their preparation and their use as catalysts INST FRANCAIS DU PETROLE (FR) 2003-04-16 EP claimed
US-6503662-B1 Tert-butylbenzene derivative prevents oxidation and decomposition of solvent at the time of charging which causes decreased battery characteristics UBE INDUSTRIES, LTD. (JP) 2003-01-07 US claimed
CN-1290974-A Nonaqueous electrolyte solution and lithium secondary battery using same UBE INDUSTRIES (JP) 2001-04-11 CN claimed
EP-0710638-B1 Rhenium and aluminium containing catalytic compositions, their preparation and use for the metathesis of olefins INST FRANCAIS DU PETROLE (FR) 1999-02-10 EP claimed
EP-0710639-B1 New supported compounds containing rhenium and aluminium, their preparation and use for the metathesis of olefins INST FRANCAIS DU PETROLE (FR) 1998-08-19 EP claimed
EP-0714902-A2 Rhenium and aluminium compounds, their preparation and their use as catalysts INSTITUT FRANCAIS DU PETROLE (FR) 1996-06-05 EP claimed
EP-0710639-A1 New supported compounds containing rhenium and aluminium, their preparation and use for the metathesis of olefins INSTITUT FRANCAIS DU PETROLE (FR) 1996-05-08 EP claimed
EP-0710638-A1 Rhenium and aluminium containing catalytic compositions, their preparation and use for the metathesis of olefins INSTITUT FRANCAIS DU PETROLE (FR) 1996-05-08 EP claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109927-A1 BIS (ARENE) METAL COMPLEXES AND RELATED METHODS FHIT, NBAS, NCLN ACHE 916/4885HDAC4 3380/4885HDAC2 1421/4885
US-20230278958-A1 TRICYCLIC HETEROCYCLES YAP1, TERF2IP, TEAD1 ACHE 4878/4885HDAC4 1943/4885HDAC2 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.