Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333770 | 0.81 | TSHR (0.36) | ALDH1A1MAPTKDM4EMAOB | |
| SCHEMBL8388374 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EMAOB | |
| SCHEMBL8387402 | 0.80 | NFE2L2 (0.33) | — | |
| SCHEMBL12330401 | 0.78 | ALDH1A1 (0.33) | ALDH1A1MAPTKDM4EMAOB | |
| SCHEMBL17535782 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MAPTKDM4EMAOB | |
| SCHEMBL8389851 | 0.75 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4E | |
| SCHEMBL17535566 | 0.74 | — | — | |
| SCHEMBL658523 | 0.73 | ALDH1A1 (0.32) | ALDH1A1MAPTKDM4EEZH2 | |
| SCHEMBL8388052 | 0.72 | CCR8 (0.38) | ALDH1A1MAPTKDM4EMAOB | |
| SCHEMBL17027090 | 0.70 | KDM4E (0.37) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874579-A | Insecticidal substituted-2.4-diaminoquinazolines related applications | FMC CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| US-5616718-A | USEFUL FOR MAKING 2,4-DIAMINOQUINAZOLINES; INSECTICIDES | FMC CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |
| US-5534518-A | Insecticidal substituted-2,4-diaminoquinazolines | FMC CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |