Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391067 | 1.00 | MAPT (0.50) | MAPTALDH1A1KMT2ALMNAHSD17B3 | |
| SCHEMBL4005429 | 0.81 | MAPT (0.61) | MAPTALDH1A1KMT2ALMNAHSD17B3 | |
| SCHEMBL5950254 | 0.79 | AKR1C3 (0.62) | MAPTALDH1A1KMT2ALMNAHSD17B3 | |
| SCHEMBL5950256 | 0.79 | AKR1C3 (0.62) | MAPTALDH1A1KMT2ALMNAHSD17B3 | |
| SCHEMBL7071418 | 0.79 | AKR1C3 (0.46) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL7071420 | 0.79 | AKR1C3 (0.46) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL13464635 | 0.78 | MAPT (0.50) | MAPTALDH1A1KMT2ALMNAHSD17B3 | |
| SCHEMBL7071034 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL7067160 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL8387734 | 0.76 | KDM4E (0.53) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972839-A | MIXTURE WITH PLANT SAFENING AGENT | HOECHST SCHERING AGREVO GMBH (DE) | 1999-10-26 | — | — | US | claimed |