Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394020 | 0.91 | HDAC3 (0.53) | NAMPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8392955 | 0.90 | ALDH1A1 (0.49) | RAB9ANPC1PARP1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL8397093 | 0.90 | HDAC3 (0.52) | NAMPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8392055 | 0.89 | ALDH1A1 (0.48) | RAB9ANPC1PARP1LMNAMAPT | |
| SCHEMBL8394082 | 0.84 | NPC1 (0.53) | NAMPTEPHX2RAB9ANPC1ALDH1A1 | |
| SCHEMBL8392758 | 0.84 | NPC1 (0.49) | NAMPTRAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8395527 | 0.84 | NPC1 (0.52) | NAMPTEPHX2RAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8394147 | 0.83 | NPC1 (0.48) | NAMPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL8395856 | 0.80 | HDAC2 (0.51) | ALDH1A1 | |
| SCHEMBL8395271 | 0.77 | ALDH1A1 (0.58) | MCHR1NAMPTRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690851-B1 | GUANIDINE DERIVATIVES USEFUL IN THERAPY | ASTRA AB (SE) | 1999-05-19 | — | — | EP | claimed |