Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244424 | 1.00 | THRB (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL201684 | 0.97 | ALDH1A1 (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL198421 | 0.97 | ALDH1A1 (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL9197519 | 0.92 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL1829226 | 0.92 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL7514432 | 0.92 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL817188 | 0.92 | ALDH1A1 (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL310698 | 0.92 | ALDH1A1 (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL815676 | 0.92 | ALDH1A1 (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL817195 | 0.92 | ALDH1A1 (0.39) | THRBMEN1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5868961-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-02-09 | — | — | US | disclosed |