Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042400 | 0.80 | NPSR1 (0.50) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL10627909 | 0.78 | NPSR1 (0.48) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL8393643 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL8394855 | 0.76 | ALDH1A1 (0.43) | NPSR1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL5167275 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL1386191 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL8397256 | 0.71 | NPSR1 (0.46) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL966679 | 0.71 | KMT2A (0.50) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL9762691 | 0.71 | NPSR1 (0.52) | NPSR1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL8396656 | 0.71 | NPSR1 (0.46) | NPSR1ALDH1A1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |