Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042400 | 0.80 | NPSR1 (0.50) | NPSR1ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL10627909 | 0.78 | NPSR1 (0.48) | NPSR1ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL8393641 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL8394857 | 0.76 | ALDH1A1 (0.60) | NPSR1ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL5167275 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL764342 | 0.75 | NPSR1 (0.50) | NPSR1ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL75883 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL28237283 | 0.75 | NPSR1 (0.50) | NPSR1ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL75885 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL28148401 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570723-A | Pyrazolopyrimidine derivative, its preparation method, and its use in preparation of medicines | UNIV SICHUAN | 2014-02-12 | — | — | CN | disclosed |
| CN-103159801-A | N-ferrocenyl-N'-aryl urea compound and applications thereof | HUAYUAN LIKANG BIOLOG TECHNOLOGY BEIJING CO LTD | 2013-06-19 | — | — | CN | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |