Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23673724 | 1.00 | USP2 (0.71) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL10005231 | 0.93 | KDM4E (0.64) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL8352923 | 0.89 | ALDH1A1 (0.59) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL12761114 | 0.89 | USP2 (0.59) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL11154511 | 0.87 | KDM4E (0.58) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL9751080 | 0.86 | ALDH1A1 (0.57) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL8195163 | 0.86 | HTT (0.59) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL8193195 | 0.86 | HTT (0.59) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL18181946 | 0.85 | SMN1; SMN2 (0.59) | USP2ALDH1A1KDM4EALOX15HTT | |
| SCHEMBL13924017 | 0.85 | KDM4E (0.55) | USP2ALDH1A1KDM4EALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874573-A | Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy | CONCAT, INC. (US) | 1999-02-23 | — | — | US | claimed |