Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 5/20 | 0.33 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696047 | 0.93 | HDAC11 (0.36) | PTGER4PTGER2PTGER3CNR2FAAH | |
| SCHEMBL8394410 | 0.87 | RARA (0.39) | CNR2FAAHHDAC11RARARARB | |
| SCHEMBL8394152 | 0.86 | PTGER4 (0.46) | PTGER4PTGER2PTGER3CNR2FAAH | |
| SCHEMBL8398155 | 0.85 | CNR2 (0.34) | CNR2FAAHHDAC11RARARARB | |
| SCHEMBL8396527 | 0.83 | PLA2G4A (0.35) | CNR2FAAHHDAC11RARARARB | |
| SCHEMBL8397766 | 0.83 | RARA (0.46) | CNR2FAAHHDAC11RARARARB | |
| SCHEMBL8694379 | 0.81 | HDAC11 (0.33) | PTGER4PTGER2PTGER3HDAC11RARA | |
| SCHEMBL8397789 | 0.81 | CNR2 (0.35) | CNR2FAAHRARARARBRARG | |
| SCHEMBL8690499 | 0.81 | RARA (0.48) | PTGER4PTGER2PTGER3CNR2FAAH | |
| SCHEMBL8397835 | 0.80 | KDM4E (0.43) | CNR2FAAHRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | claimed |
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |