Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.39 |
| ▸ | RARA | P10276 | 8/20 | 0.35 |
| ▸ | RARG | P13631 | 5/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394258 | 0.84 | RARA (0.35) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8457127 | 0.80 | RARB (0.48) | IKBKBRARARARGRARBMEN1 | |
| Hydrochloric Acid SCHEMBL8458532 | 0.79 | RARB (0.47) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8397880 | 0.77 | RARA (0.48) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8397927 | 0.76 | IKBKB (0.33) | IKBKBRARAS1PR1 | |
| SCHEMBL8394413 | 0.76 | RARA (0.41) | IKBKBRARARARGRARBHDAC11 | |
| SCHEMBL8320658 | 0.76 | RARB (0.52) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8396578 | 0.75 | CHEK1 (0.48) | MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL8433273 | 0.74 | RARA (0.45) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8399150 | 0.74 | RARA (0.40) | IKBKBRARARARGRARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |