Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437131 | 0.92 | KMT2A (0.56) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL29401421 | 0.92 | KMT2A (0.56) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL31437099 | 0.92 | KMT2A (0.56) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL3728827 | 0.92 | KMT2A (0.56) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL1738761 | 0.92 | KMT2A (0.56) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL260631 | 0.91 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL178733 | 0.91 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL178698 | 0.91 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL29359997 | 0.91 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL29528567 | 0.91 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287653-A1 | METHOD FOR PRODUCING INHIBITORS AND INHIBITORS FORMED THEREFROM | THE UNIVERSITY OF AKRON (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080286815-A1 | SPECTROPHOTOMETRIC ASSAY FOR HUMAN HISTONE DEACETYLASE 8 | THE UNIVERSITY OF AKRON (US) | 2008-11-20 | — | — | US | disclosed |