Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 4/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396230 | 0.91 | AGTR2 (0.67) | AGTR2AGTR1PPARG | |
| SCHEMBL8395396 | 0.91 | AGTR2 (0.55) | AGTR2AGTR1PPARG | |
| SCHEMBL9040902 | 0.89 | AGTR2 (0.49) | AGTR2AGTR1 | |
| SCHEMBL8393293 | 0.88 | AGTR2 (0.72) | AGTR2AGTR1PPARG | |
| SCHEMBL8391387 | 0.88 | AGTR1 (0.59) | AGTR2AGTR1 | |
| SCHEMBL8393408 | 0.87 | AGTR2 (0.53) | AGTR2AGTR1PPARG | |
| SCHEMBL8395042 | 0.86 | AGTR2 (0.57) | AGTR2AGTR1PPARG | |
| SCHEMBL8396220 | 0.86 | AGTR1 (0.77) | AGTR2AGTR1PPARG | |
| SCHEMBL8392643 | 0.84 | AGTR2 (0.56) | AGTR2AGTR1PPARG | |
| SCHEMBL8396783 | 0.84 | PPARG (0.78) | AGTR2AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |