Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395126 | 0.85 | TSHR (0.50) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL15430918 | 0.82 | TSHR (0.50) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL25523467 | 0.81 | TSHR (0.46) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL12111975 | 0.81 | TSHR (0.56) | ALDH1A1TSHRSMN1; SMN2TDP1TP53 | |
| SCHEMBL13384514 | 0.79 | TSHR (0.50) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL13002443 | 0.78 | SMN1; SMN2 (0.49) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL17123547 | 0.78 | TSHR (0.48) | ALDH1A1TSHRSMN1; SMN2TDP1TP53 | |
| SCHEMBL996238 | 0.78 | TSHR (0.48) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL14515640 | 0.76 | TSHR (0.53) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL28259378 | 0.76 | TSHR (0.50) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702500-B2 | Biomedical devices | BAUSCH + LOMB IRELAND LIMITED (IE) | 2023-07-18 | — | — | US | disclosed |
| US-8389597-B2 | High water content ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2013-03-05 | — | — | US | disclosed |
| US-8377464-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120157565-A1 | Polymerizable Surfactants and Their Use as Device Forming Comonomers | BAUSCH HEALTH US, LLC | 2012-06-21 | — | — | US | disclosed |
| US-8197841-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| US-20120141408-A1 | High Water Content Ophthalmic Devices | SOLTA MEDICAL, INC. | 2012-06-07 | — | — | US | disclosed |
| US-8138290-B2 | High water content ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090191256-A1 | HIGH WATER CONTENT OPHTHALMIC DEVICES | BAUSCH HEALTH AMERICAS, INC. | 2009-07-30 | — | — | US | disclosed |
| US-20090142292-A1 | Method For The Mitigation of Symptoms of Dry Eye | BAUSCH & LOMB INCORPORATED | 2009-06-04 | — | — | US | disclosed |
| US-20090142387-A1 | Method For Inhibiting Attachment Of Microorganisms To Biomedical Devices | BAUSCH & LOMB INCORPORATED | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141408-A1 | High Water Content Ophthalmic Devices | AQP1, AQP3, AQP4 | ALDH1A1 2955/4885TSHR 2809/4885SMN1; SMN2 4511/4885 |
| US-20090142387-A1 | Method For Inhibiting Attachment Of Microorganisms To Biomedical Devices | MIF, MSN, NAPA | ALDH1A1 1667/4885TSHR 2263/4885SMN1; SMN2 3946/4885 |
| US-20090142292-A1 | Method For The Mitigation of Symptoms of Dry Eye | CSTB, CFB, MSN | ALDH1A1 2855/4885TSHR 253/4885SMN1; SMN2 4036/4885 |
| US-20090191256-A1 | HIGH WATER CONTENT OPHTHALMIC DEVICES | AQP1, AQP3, AQP4 | ALDH1A1 2955/4885TSHR 2809/4885SMN1; SMN2 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.