Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395198 | 0.92 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8399170 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTLMNATDP1 | |
| SCHEMBL8399331 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8395843 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8397982 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8400187 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTLMNATDP1 | |
| SCHEMBL8399091 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTLMNATDP1 | |
| SCHEMBL8399169 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8400489 | 0.86 | MAPK1 (0.44) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8399007 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |