Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.70 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.67 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393270 | 0.94 | AGTR1 (0.71) | PPARGAGTR1AGTR2L3MBTL1 | |
| SCHEMBL8391300 | 0.92 | PPARG (0.69) | PPARGAGTR1AGTR2 | |
| SCHEMBL8392458 | 0.87 | PPARG (0.69) | PPARGAGTR1AGTR2 | |
| SCHEMBL8392654 | 0.87 | PPARG (0.53) | PPARGAGTR1AGTR2L3MBTL1 | |
| SCHEMBL9040948 | 0.85 | L3MBTL1 (0.55) | PPARGAGTR1AGTR2L3MBTL1 | |
| SCHEMBL8393485 | 0.84 | PPARG (0.76) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396958 | 0.82 | PPARG (1.00) | PPARGAGTR1AGTR2 | |
| SCHEMBL8393405 | 0.82 | PPARG (0.84) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396864 | 0.82 | PPARG (0.72) | PPARGAGTR1AGTR2 | |
| SCHEMBL8393455 | 0.81 | AGTR1 (0.54) | PPARGAGTR1AGTR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |