Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394481 | 1.00 | EPHX1 (0.53) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8396002 | 1.00 | EPHX1 (0.53) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8391395 | 1.00 | EPHX1 (0.53) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8391573 | 1.00 | EPHX1 (0.53) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8392281 | 0.98 | TPSAB1 (0.52) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8392284 | 0.96 | TPSAB1 (0.55) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8395040 | 0.95 | TPSAB1 (0.56) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8396720 | 0.95 | TPSAB1 (0.52) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8396537 | 0.93 | TPSAB1 (0.54) | EPHX1TPSAB1TPSD1TPSG1HTT | |
| SCHEMBL8392471 | 0.90 | SIGMAR1 (0.48) | EPHX1TPSAB1TPSD1TPSG1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |