Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.67 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944346 | 0.92 | AGTR2 (0.67) | AGTR1AGTR2 | |
| SCHEMBL8392138 | 0.92 | AGTR1 (0.79) | AGTR1AGTR2PPARG | |
| SCHEMBL8944781 | 0.92 | AGTR1 (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL9041882 | 0.91 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL8395922 | 0.90 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL8393396 | 0.89 | AGTR1 (0.84) | AGTR1AGTR2 | |
| SCHEMBL8392186 | 0.88 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL8392213 | 0.86 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9040681 | 0.86 | AGTR1 (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL9040791 | 0.85 | AGTR2 (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |