Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.59 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22369614 | 0.81 | ELANE (0.86) | ELANEPRTN3 | |
| SCHEMBL23135278 | 0.80 | ELANE (0.66) | ELANEPRTN3MEN1KMT2AALDH1A1 | |
| SCHEMBL2831697 | 0.80 | MAPT (0.58) | ELANEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19201617 | 0.79 | ELANE (0.63) | ELANEPRTN3MEN1KMT2A | |
| SCHEMBL11810932 | 0.77 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL20679035 | 0.77 | ELANE (0.61) | ELANEPRTN3MEN1KMT2A | |
| SCHEMBL28702876 | 0.77 | L3MBTL1 (0.68) | ELANEMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1666256 | 0.77 | ELANE (0.66) | ELANEPRTN3KMT2AALDH1A1 | |
| SCHEMBL11808720 | 0.77 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL28098390 | 0.76 | KMT2A (0.54) | ELANEMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11263778-A | — | — | None | — | — | JP | disclosed |
| JP-H11263778-A | AMINOMETHYLENEPYRIMIDINE DERIVATIVE, ITS PRODUCTION AND USE | CHEMIPROKASEI KAISHA LTD | 1999-09-28 | — | — | JP | disclosed |