SCHEMBL8395443

SCHEMBL8395443

CC(c1ccccc1)c1ccccc1Oc1ccc(C(C)c2ccccc2)c([O])c1C(C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.36
VKORC1 Q9BQB6 1/20 0.34
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
P2RX3 P56373 1/20 0.31
P2RX2 Q9UBL9 1/20 0.31
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTR2A P28223 2/20 0.31
SLC6A4 P31645 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19172035 0.82 TYR (0.44) TYRIDO1TDO2P2RX3P2RX2
SCHEMBL5480077 0.79 TYR (0.43) TYRVKORC1IDO1TDO2LMNA
SCHEMBL9340368 0.75 TYR (0.47) TYRLMNA
Sulfuric Acid SCHEMBL28706711 0.75 TYR (0.41) TYRVKORC1LMNAL3MBTL1
Methacrylic Acid SCHEMBL5095484 0.73 HPGD (0.40) TYRIDO1TDO2LMNAL3MBTL1
SCHEMBL5941442 0.71 IDO1 (0.56) TYRIDO1TDO2L3MBTL1
SCHEMBL28670888 0.71 IDO1 (0.56) TYRIDO1TDO2L3MBTL1
SCHEMBL868867 0.71 PTGS2 (0.53) TYRLMNA
SCHEMBL10541465 0.69 TYR (0.46) TYRIDO1TDO2LMNAL3MBTL1
SCHEMBL8846909 0.68 TYR (0.42) TYRIDO1TDO2LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36128-E STABILIZER FOR ORGANIC COMPOUNDS ALBEMARLE CORPORATION (US) 1999-03-02 US disclosed
US-4912155-A Containing substituted aryl group ETHYL CORPORATION (US) 1990-03-27 US disclosed