Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 4/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396211 | 0.88 | AKR1B1 (0.47) | AKR1B1AKR1A1 | |
| SCHEMBL8395478 | 0.88 | AKR1B1 (0.42) | AKR1B1AKR1A1 | |
| SCHEMBL8397910 | 0.88 | AKR1B1 (0.42) | AKR1B1AKR1A1MEN1KMT2A | |
| SCHEMBL8397104 | 0.85 | AKR1B1 (0.49) | AKR1B1AKR1A1 | |
| SCHEMBL8396047 | 0.83 | AKR1B1 (0.39) | AKR1B1AKR1A1 | |
| SCHEMBL8398181 | 0.83 | AKR1B1 (0.44) | AKR1B1AKR1A1 | |
| SCHEMBL8395622 | 0.82 | KDM4E (0.41) | AKR1B1NOS1HPGDMEN1NPC1 | |
| SCHEMBL8399216 | 0.81 | AKR1B1 (0.44) | AKR1B1AKR1A1 | |
| SCHEMBL8399113 | 0.81 | NOS1 (0.44) | AKR1B1NOS1HPGDMEN1NPC1 | |
| SCHEMBL8398952 | 0.81 | AKR1B1 (0.44) | AKR1B1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |