SCHEMBL8742010

SCHEMBL8742010

COCC(COC)COC(=O)/C=C\C(=O)OCC(COC)COC

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
HCAR2 Q8TDS4 9/20 0.43
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 2/20 0.38
MAPT P10636 2/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29084605 1.00 ATM (0.46) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL27127631 0.92 HCAR2 (0.57) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL8742013 0.92 HCAR2 (0.57) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL29084608 0.92 HCAR2 (0.57) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL8395663 0.85 TSHR (0.61) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL21677119 0.85 TSHR (0.61) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL1453623 0.78 TSHR (0.53) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL11745052 0.78 TSHR (0.53) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL1884148 0.76 HCAR2 (0.42) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL1880535 0.76 HCAR2 (0.42) ATMHCAR2KEAP1NFE2L2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5635577-A MIXTURES CONTAINING ORGANOSILICON COMPOUNDS OR POLYMERS SUBSTITUTED BY HYDROCARBON(PARTIALLY UNSATURATED) RADICALS, PLATINUM CATALYST, CATALYST INHIBITOR TO PREVENT ROOM TEMPERATURE REACTIONS AND A PERESTER INHIBITOR GENERAL ELECTRIC COMPANY (US) 1997-06-03 US claimed
US-5290885-A Hydrosilylation reaction DOW CORNING CORPORATION (US) 1994-03-01 US claimed
US-5248739-A Adhesive tapes DOW CORNING CORPORATION (US) 1993-09-28 US claimed
US-20260117090-A1 SILICONE POLYETHER WITH BRANCHED PENDANT POLYETHER GROUP DOW SILICONES CORP (US) 2026-04-30 US disclosed
US-20260117089-A1 SILICONE POLYETHER WITH LINEAR PENDANT POLYETHER GROUP DOW SILICONES CORP (US) 2026-04-30 US disclosed
EP-4330340-B1 HYDROSILYLATION REACTION CURED SILICONE PRESSURE SENSITIVE ADHESIVE, COMPOSITION AND METHOD FOR ITS PREPARATION, AND USE IN FLEXIBLE DISPLAY DEVICE DOW SILICONES CORP (US) 2026-02-25 EP disclosed
US-12516229-B2 Printable silicone composition and methods for its preparation and use DOW SILICONES CORPORATION (US) 2026-01-06 US disclosed
EP-4642856-A1 CURABLE SILICONE COMPOSITION Dow Silicones Corporation (US) 2025-11-05 EP disclosed
US-12460114-B2 Hydrosilylation reaction cured silicone pressure sensitive adhesive, composition and method for its preparation, and use in a flexible display device DOW SILICONE CORPORATION (US) 2025-11-04 US disclosed
WO-2025226433-A1 SILICON RELEASE COATING WITH GREASE AND WATER BARRIER PROPERTIES DOW SILICONES CORPORATION (US) 2025-10-30 WO disclosed
EP-4288503-B1 PRINTABLE SILICONE COMPOSITION AND METHODS FOR ITS PREPARATION AND USE DOW SILICONES CORP (US) 2025-01-29 EP disclosed
EP-2978795-A1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES Dow Corning Corporation (US) 2016-02-03 EP disclosed
WO-2014160975-A1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES DOW CORNING CORPORATION (US) 2014-10-02 WO disclosed
EP-0664328-B1 Moisture-curable silicone pressure sensitive adhesives DOW CORNING (US) 1997-10-08 EP disclosed
US-5658629-A BASE LAYER HAVING ONE SIDE IMPERVIOUS TO WATER VAPOR AND SILICONE MIGRATION AND SECOND SIDE PERMEABLE TO WATER VAPOR MORGAN ADHESIVES COMPANY (US) 1997-08-19 US disclosed
US-5545700-A OBTAINED BY THERMALLY CURING MIXTURE OF ENDCAPPED POLYSILICATE-POLYSILOXANE, ALKENYL-FUNCTIONAL POLYSILOXANE, POLYHYDROGENSILOXANE, ALKENETRIALKOXYSILANE, PLATINUM CONTAINING CATALYST, MOISTURE CURING CATALYST DOW CORNING CORPORATION (US) 1996-08-13 US disclosed
EP-0664328-A1 Moisture-curable silicone pressure sensitive adhesives DOW CORNING CORPORATION (US) 1995-07-26 EP disclosed
EP-0537784-B1 Silicone pressure sensitive adhesives having enhanced adhesion to low energy substrates DOW CORNING (US) 1995-03-01 EP disclosed
US-5248739-A Adhesive tapes DOW CORNING CORPORATION (US) 1993-09-28 US disclosed
EP-0537784-A1 Silicone pressure sensitive adhesives having enhanced adhesion to low energy substrates DOW CORNING CORPORATION (US) 1993-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117089-A1 SILICONE POLYETHER WITH LINEAR PENDANT POLYETHER GROUP SMC3, SGMS2, SMC2 ATM 2302/4885HCAR2 3018/4885KEAP1 3310/4885
US-20260117090-A1 SILICONE POLYETHER WITH BRANCHED PENDANT POLYETHER GROUP COG3, COG2, SMC3 ATM 2226/4885HCAR2 2613/4885KEAP1 3124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.