Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7608431 | 0.99 | HMGB1 (0.54) | HMGB1CYP3A4MEN1KMT2AMMP2 | |
| Trifluoroacetic Acid SCHEMBL6289474 | 0.93 | HMGB1 (0.48) | HMGB1CYP3A4MEN1KMT2AMMP2 | |
| SCHEMBL6290071 | 0.78 | CYP3A4 (0.56) | CYP3A4CA1CA2 | |
| Hydrochloric Acid SCHEMBL6289116 | 0.78 | CYP3A4 (0.44) | CYP3A4MEN1KMT2AMMP2TPSAB1 | |
| Hydrochloric Acid SCHEMBL6292872 | 0.76 | CYP3A4 (0.43) | CYP3A4MEN1KMT2AMMP2TPSAB1 | |
| SCHEMBL11434850 | 0.74 | MEN1 (0.83) | CYP3A4MEN1KMT2AMMP2TPSAB1 | |
| SCHEMBL14623873 | 0.74 | MEN1 (0.83) | CYP3A4MEN1KMT2AMMP2TPSAB1 | |
| SCHEMBL13973365 | 0.74 | CA2 (0.57) | CYP3A4MEN1KMT2ATPSAB1GAA | |
| Hydrochloric Acid SCHEMBL6292871 | 0.73 | HMGB1 (0.51) | HMGB1KMT2AMMP2ALBHPGD | |
| SCHEMBL23773420 | 0.73 | ALOX5 (0.62) | HMGB1MMP2HTTALBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915832-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005627-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX, INC. (US) | 1998-02-12 | — | — | WO | disclosed |