Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393707 | 0.91 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8391984 | 0.89 | AGTR2 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9041884 | 0.89 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8393563 | 0.88 | PPARG (0.60) | AGTR1AGTR2 | |
| SCHEMBL8391119 | 0.87 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8944526 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8397226 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8394532 | 0.86 | — | — | |
| SCHEMBL8394802 | 0.85 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8394992 | 0.85 | PPARG (0.73) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |