Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSPO | P30536 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400564 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSPOKDM4EKMT2APOLB | |
| SCHEMBL8395613 | 0.88 | AKR1B1 (0.36) | ALDH1A1KMT2APOLBTDP1TSHR | |
| SCHEMBL8395480 | 0.87 | AKR1B1 (0.40) | KMT2APOLBTSHR | |
| SCHEMBL8398844 | 0.86 | AKR1B1 (0.42) | ALDH1A1TSPOKDM4EKMT2APOLB | |
| SCHEMBL8518212 | 0.85 | AKR1B1 (0.34) | — | |
| SCHEMBL8396414 | 0.85 | AKR1B1 (0.36) | KMT2APOLBTSHR | |
| SCHEMBL8399154 | 0.85 | AKR1B1 (0.35) | ALDH1A1KDM4EKMT2APOLBTSHR | |
| SCHEMBL8396110 | 0.85 | AKR1B1 (0.41) | ALDH1A1TSPOKDM4EKMT2ATDP1 | |
| SCHEMBL8399078 | 0.84 | AKR1B1 (0.46) | — | |
| SCHEMBL8395274 | 0.84 | AKR1B1 (0.37) | ALDH1A1POLBTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |